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Peptides  >  Neuropeptides  >>  QF-ERP7, FRET

Product Name QF - ERP7, FRET
Abz - GGFLRRV - EDDnp
Size 0.5 mg
Catalog # AS-62728
US$ $143
Purity % Peak Area By HPLC ≥ 95%
Description

This FRET peptide, structurally related to enkephalins, proved to be suitable for assaying the endooligopeptidase A activity. Endooligopeptidase A is a putative neuropeptide-metabolizing enzyme. It converts small enkephalin-containing peptides into the corresponding enkephalins and inactivates biopeptides such as bradykinin and neurotensin in vitro. The enzyme only splits the L-R bond, a reaction efficiently blocked by anti-endooligopeptidase A antibodies. Evidence based on the action of inhibitors and on the analysis of QF-ERP7 fragments demonstrated that endooligopeptidase A contributes 100% of the QF-ERP7 cleaving activity found in the cytosol of rabbit brain homogenates.

Storage -20C
References Juliano, L. et al. Biochem. Biophys. Res. Commun. 173, 647 (1990); Ferro, E. et al. J. Cell Biochem. 57, 311 (2004).
Molecular Weight 1132.4
Sequence
(One-Letter Code)
Abz-GGFLRRV-EDDnp
Sequence
(Three-Letter Code)
Abz - Gly - Gly - Phe - Leu - Arg - Arg - Val - EDDnp
     
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