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Peptides  >  Signal Transduction Peptides  >>  eNOS (494-513), Calmodulin Binding Domain

Product Name eNOS (494 - 513), Calmodulin Binding Domain
RKKTFKEVANAVKISASLMG
Size 1 mg
Catalog # 63768
US$ $121
Purity % Peak Area By HPLC ≥ 95%
Description

This is amino acids 494 to 513 fragment of endothelial nitric oxide synthase (eNOS) calmodulin (CaM)-binding region. The enzyme NOS is exquisitely regulated in vivo by the calcium sensor protein calmodulin to control production of NO, a key signaling molecule and cytotoxin.

Storage -20C
References Aoyagi, M. et al. EMBO J. 22, 766 (2003); Frederick, K. et al. Nature 448, 325 (2007).
Molecular Weight 2178.6
Sequence
(One-Letter Code)
RKKTFKEVANAVKISASLMG
Sequence
(Three-Letter Code)
H - Arg - Lys - Lys - Thr - Phe - Lys - Glu - Val - Ala - Asn - Ala - Val - Lys - Ile - Ser - Ala - Ser - Leu - Met - Gly - OH
Product Citations Nygaard, E. et al. (2011). Structural Modeling and Electron Paramagnetic Resonance Spectroscopy of the Human Na+/H+ Exchanger Isoform 1, NHE1. J Biol Chem 286, 634.
     
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