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Peptides  >  Cancer Research Peptides  >>  Neuropilin-1 (NRP-1) Antagonist; EG3287

Product Name Neuropilin - 1 (NRP - 1) Antagonist; EG3287
SCKNTDSRCKARQLELNERTCRCDKPRR (Disulfide bridge 2 - 20 and 9 - 22)
Size 1 mg
Catalog # AS-62840-1
US$ $484
Purity % Peak Area By HPLC ≥ 95%
Description

This is EG3287, a peptide fragment based on the Neuropilin-1 (NRP-1) Vascular Endothelial Growth Factor A (VEGF-A) binding site, located on exons 7 and 8. EG3287 is a NRP-1 antagonist and contains an C-terminal Arg essential for inhibition of VEGF165 binding. As a result, EG3287 decreases tumor angiogenesis and growth.

Detailed Information Material Safety Data Sheets (MSDS)
Storage -20C
References Starzec, A. et al. Peptides 28, 2397 (2007).
Molecular Weight 3363.9
Sequence
(One-Letter Code)
SCKNTDSRCKARQLELNERTCRCDKPRR (Disulfide bridge 2-20 and 9-22)
Sequence
(Three-Letter Code)
H - Ser - Cys - Lys - Asn - Thr - Asp - Ser - Arg - Cys - Lys - Ala - Arg - Gln - Leu - Glu - Leu - Asn - Glu - Arg - Thr - Cys - Arg - Cys - Asp - Lys - Pro - Arg - Arg - OH (Disulfide bridge 2 - 20 and 9 - 22)
     
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