This peptide is derived from amino acid residues 57-68 of a9-gliadin and represents an immunodominant epitope that has been shown to elicit HLA-DQ2-restricted T-cell responses in celiac patients. This epitope is resistant to pancreatic proteolysis.
Storage
-20°C
References
Arentz-Hansen, H. et al. J Exp Med191, 603 (2000). Hausch, F. et al. Am J Physiol Gastrointest Liver Physiol283, 996 (2002). Mamone, G. et al. J Chromatogr B855, 236 (2007).
Molecular Weight
1455.7
Sequence (One-Letter Code)
QLQPFPQPQLPY
Sequence (Three-Letter Code)
H - Gln - Leu - Gln - Pro - Phe - Pro - Gln - Pro - Gln - Leu - Pro - Tyr - OH