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Peptides  >  Histones  >  Histone H3 Peptides  >>  [Cit2]-Histone H3 (1-21)-GGK(Biotin)

Product Name [Cit2] - Histone H3 (1 - 21) - GGK(Biotin)
A - Cit - TKQTARKSTGGKAPRKQLAGG - K(Biotin)
Size 0.25 mg
Catalog # AS-65237-025
US$ $115
Purity % Peak Area By HPLC ≥ 95%
Description

This peptide is histone H3 (1-21) with deimination at Arg2, converting it to Cit (citrulline). It is biotinylated through a C-terminal GGK linker. Arg2 is deiminated by peptidyl arginine deiminase 4 (PADI4). Conversion to citrulline blocks methylation at this site and inhibits transcriptional activation. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form.

Storage -20C
References Cuthbert, G. et al. Cell 118, 545 (2004).
Molecular Weight 2724.2
Sequence
(One-Letter Code)
A-Cit-TKQTARKSTGGKAPRKQLAGG-K(Biotin)
Sequence
(Three-Letter Code)
H - Ala - Cit - Thr - Lys - Gln - Thr - Ala - Arg - Lys - Ser - Thr - Gly - Gly - Lys - Ala - Pro - Arg - Lys - Gln - Leu - Ala - Gly - Gly - Lys(Biotin) - OH
     
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