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Peptides  >  Cancer Research Peptides  >>  Nuclear Factor (Erythroid-derived 2)like 2 (74-87); Nrf2 (74-87); NFE2L2 (74-87)
Product Name Nuclear Factor (Erythroid - derived 2)like 2 (74 - 87); Nrf2 (74 - 87); NFE2L2 (74 - 87)
Size 5 mg
Catalog # 65341
US$ $280
Purity % Peak Area By HPLC ≥ 95%
Description

This peptide is derived from the Neh2 domain of nuclear factor (erythroid-derived 2)-like 2, or Nrf2. Nrf2 is a bZIP transcription factor that regulates the expression of antioxidative and cytoproptective genes. The DxETGE motif of this peptide binds Keap1 Kelch adaptor protein and displaces Nrf2 from Keap1.
Storage -20°C
References Yokota, S. et al. Biochem Pharmacol 81, 289 (2011); Lo, S-C. et al. EMBO J 25, 3605 (2006).
Molecular Weight 1631.8
Sequence
(One-Letter Code)		 LQLDEETGEFLPIQ
Sequence
(Three-Letter Code)		 H - Leu - Gln - Leu - Asp - Glu - Glu - Thr - Gly - Glu - Phe - Leu - Pro - Ile - Gln - OH
     
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