This peptide is derived from thrombospondin and represents a binding motif responsible for thrombospondin-CD36 interaction. It is cyclized through a disulfide bond. Thrombospondin is a matrix-bound glycoprotein involved in cancer metastasis, tumor adhesion, and angiogenesis. This peptide has been shown to competitively inhibit platelet aggregation and tumor metastasis.
Storage
-20°C
References
Wakiyama, T. et al. Histol Histopathol16, 345 (2001); Tsuzynski, G. et al. J Cell Biol120, 513 (1993); Asch, A. et al. Biochem Biophys Res Commun182, 1208 (1992).
Molecular Weight
566.7
Sequence (One-Letter Code)
CSVTCG (S-S Bonded)
Sequence (Three-Letter Code)
H - Cys - Ser - Val - Thr - Cys - Gly - OH (S - S Bonded)
