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Perkin Elmer Storefronts  >  Histone H3 Peptides  >>  Histone H3 (1-21), Biotinylated

Product Name Histone H3 (1 - 21), Biotinylated
Size 1 mg
Catalog # AS-61702
US$ $225
Purity % Peak Area By HPLC ≥ 95%

This sequence corresponds to the first 21 amino acids of the NH2 terminal of histone H3 followed by a GG linker and a biotinylated lysine. This peptide was used to investigate the characteristics and mechanisms of ethanol-induced histone H3 acetylation in rat hepatocytes. Immunocytochemical and immunoblot analyses revealed that ethanol treatment significantly increased H3 acetylation at Lys9 with negligible effects at Lys14, 18, and 23.

Detailed Information Datasheet
Material Safety Data Sheets (MSDS)
Storage -20C
References Park, P. et al. Am. J. Physiol. Gastrointest. Liver Physiol. 289, G1124 (2005).
Molecular Weight 2723.2
(One-Letter Code)
(Three-Letter Code)
Ala - Arg - Thr - Lys - Gln - Thr - Ala - Arg - Lys - Ser - Thr - Gly - Gly - Lys - Ala - Pro - Arg - Lys - Gln - Leu - Ala - Gly - Gly - Lys(Biotin) - NH2
Product Citations Edwards, B. et al. (2015). Miniaturization of High-Throughput epigenetic methyltransferase assays with acoustic liquid handling JALA doi: 10.1177/2211068215610861.
Mann, M. et al. (2013). PELP1 oncogenic functions involve CARM1 regulation. Carcinogenesis 34, 1468. doi: 10.1093/carcin/bgt091.
Iwase, S. et al. (2007). The X-Linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases. J Cell. 128, 1077.
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