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Peptides  >  GPCR Peptide Ligands  >  Kisspeptin  >>  Kisspeptin-10 (Kp-10), Metastin (45-54)

Product Name Kisspeptin - 10 (Kp - 10), Metastin (45 - 54)
YNWNSFGLRF - NH2
Size 1 mg
Catalog # AS-64240
US$ $61
Description

This peptide sequence is found in residues 45 to 54 of Metastin (also referred to as Kisspeptin-10). This peptide increases plasma concentrations of GH (Growth Hormone) and LH (Luteinizing Hormone) in prepubertal dairy heifers. This peptide is the minimal sequence needed to activate GPR54 signaling, which may function in negatively regulating CXCR4s role in programming tumor metastasis. Specifically, Kisspeptin-10 inhibits signaling and chemotaxis induced by SDF-1.

Storage -20C
References Kadokawa, H. et al. J. Endocrinol. 196, 331 (2008); Kotani, M. et al. J. Biol. Chem. 276, 34631 (2001); Navenot, J.M. et al. Cancer Res, 65, 10450 (2005).
Molecular Weight 1302.5
Sequence
(One-Letter Code)
YNWNSFGLRF-NH2
Sequence
(Three-Letter Code)
H - Tyr - Asn - Trp - Asn - Ser - Phe - Gly - Leu - Arg - Phe - NH2
     
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