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Peptides  >  GPCR Peptide Ligands  >  Angiotensin  >>  Rat Renin Inhibitor Peptide, WFML Peptide

Product Name Rat Renin Inhibitor Peptide, WFML Peptide
Ac - HPFV - (Sta) - LF - NH2
Size 1 mg
Catalog # AS-60463-1
US$ $181
Purity % Peak Area By HPLC ≥ 95%

A specific rat renin inhibitor.

Storage -20°C
References Ref: Iyer, SN. et al. J. Cardiovasc. Pharmacol. 31, 464 (1998).
Molecular Weight 957.3
(One-Letter Code)
(Three-Letter Code)
Ac - His - Pro - Phe - Val - Sta - Leu - Phe - NH2
Product Citations Wang, F. et al. (2014). COX-2 mediates angiotensin II-induced (pro) renin receptor expression in the rat renal medulla. Am J Physiol Renal Physiol 307, F25. doi: 10.1152/ajprenal.00548.2013.
Westwood, BM. & MC. Chappell (2012). Divergent pathways for the angiotensin-(1–12) metabolism in the rat circulation and kidney. Peptides 35, 190. doi:10.1016/j.peptides.2012.03.025.
Chao, J. et al. (2011). Renin released from mast cells activated by circulating MCP-1 initiates the microvascular phase of the systemic inflammation of alveolar hypoxia. Am J Physiol Heart Circ Physiol 301, H2264. doi: 10.1152/ajpheart.00461.2011.
Gonzalez, A. et al. (2011). Soluble Form of the (Pro)Renin Receptor Is Augmented in the Collecting Duct and Urine of Chronic Angiotensin II–Dependent Hypertensive Rats. Hypertension 57, 859. doi: 10.1161/HYPERTENSIONAHA.110.167957.
Gonzalez, A. et al. (2011). Angiotensin II stimulates Renin in inner medullary collecting duct cells via Protein Kinase C and independent of epithelial Sodium channel and mineralocorticoid receptor activity. Hypertension 57, 594. doi: 10.1161/HYPERTENSIONAHA.110.165902.
Liu, L. et al. (2011). Increased renin excretion is associated with augmented urinary angiotensin II levels in chronic angiotensin II-infused hypertensive rats. Am J Physiol Renal Physiol 301, F1195. doi: 10.1152/ajprenal.00339.2011.
Stodola, T. et al. (2011). Characterization of the genomic structure and function of regions influencing renin and angiogenesis in the SS rat. Physiol Genomics 43, 808. doi: 10.1152/physiolgenomics.00171.2010.
Senador, D. et al. (2010). Cardiovascular interactions between losartan and fructose in mice. J Cardiovasc Pharmacol Ther 15, 68. doi: 10.1177/1074248409351409.
Trask, A. et al. (2008). Angiotensin-(1-12) is an alternate substrate for angiotensin peptide production in the heart. Am J Physiol Heart Circ Physiol 294, H2242. doi: 10.1152/ajpheart.00175.2008.
Ferrario, CM. et al. (2005). Effect of angiotensin-converting enzyme inhibition and angiotensin II receptor blockers on cardiac angiotensin-converting enzyme 2. Circulation 111, 2605. doi: 10.1161/CIRCULATIONAHA.104.510461.
Ferrario, CM. et al. (2005). Effects of renin-angiotensin system blockade on renal angiotensin-(1-7) forming enzymes and receptors. Kidney Intl 68, 2189. doi: 10.1111/j.1523-1755.2005.00675.x
Nakamura, S. et al. (2003). Angiotensin receptors contribute to blood pressure homeostasis in salt-depleted SHR. Am J Physiol Regul Integr Comp Physiol 284, R164. doi: 10.1152/ajpregu.00210.2002
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