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Peptides  >  Cyclic Peptides  >   Disulfide Cyclized Peptides  >>  Melanin Concentrating Hormone, human, mouse, rat, pig

Product Name Melanin Concentrating Hormone, human, mouse, rat, pig
DFDMLRCMLGRVYRPCWQV (Disulfide bridge: 7 - 16)
Size 1 mg
Catalog # AS-22908
US$ $215
Purity % Peak Area By HPLC ≥ 95%

Cyclic neuropeptide Malanin Concentrating Hormone (MCH) regulates feeding and complex behaviors in mammals and pigmentation in fish. The mammalian form of MHC has 19 amino acids, while the originally identified salmon MCH is 17-amino acid long (DTMRCMVGRVYRPCWEV). Mammalian MCH is expressed throughout the brain with the highest concentration in the lateral hypothalamic and zona incerta areas. In addition to regulating feeding behavior, MCH also regulates the hypothalamopituitary adrenal gland axis, modulates water and electrolyte fluxes in the gut, stimulates oxytocin secretion from isolated rat neurohypophysis, regulates of sensory processing, and modulates of monoaminergic activity in the medial preoptic area and other functions.

Detailed Information Datasheet
Material Safety Data Sheets (MSDS)
Storage -20C
References Presse, F. et al. Neurosci 71, 735 (1996)
Wang, S. et al. J Biol Chem 276, 34664 (2001), doi: 10.1074/jbc.M102601200
Molecular Weight 2386.9
(One-Letter Code)
DFDMLRCMLGRVYRPCWQV (Disulfide bridge: 7-16)
(Three-Letter Code)
H - Asp - Phe - Asp - Met - Leu - Arg - Cys - Met - Leu - Gly - Arg - Val - Tyr - Arg - Pro - Cys - Trp - Gln - Val - OH (Disulfide bridge: 7 - 16)
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