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Peptides  >  GPCR Peptide Ligands  >  PAR (Protease Activated Receptor) Peptides  >>  Protease-Activated Receptor-1, PAR-1 Antagonist, amide

Product Name Protease - Activated Receptor - 1, PAR - 1 Antagonist, amide  NEW
S - F(para - Fluoro) - Aad - LRNP - NH2
Size 1 mg
Catalog # AS-65487
US$ $185
Description

This peptide is a PAR-1 antagonist which inhibited SFLLRNP induced platelet aggregation with an IC50 of 115 uM. Antagonists specific for the thrombin receptor can be promising compounds for treatment of thrombosis.

Detailed Information Datasheet
Material Safety Data Sheets (MSDS)
Storage -20C
References Fujita, T. et al. J Biochem 126, 174 (1999).
Molecular Weight 892.9
Sequence
(One-Letter Code)
S-F(para-Fluoro)-Aad-LRNP-NH2
Sequence
(Three-Letter Code)
Ser - parafluoroPhe - Aad - Leu - Arg - Asn - Pro - NH2
     
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