Peptides

AggreSure [Pyr3] β-Amyloid (3-42), human - 0.25 mg

$365.00
Check your price
  • Cat.Number : AS-72277
  • Availability :
    In production
  • Shipping conditions : Ice fees will apply

Quantity

AggreSure™ [Pyr3] - β-Amyloid (3-42) peptide was pretreated and tested for aggregation using SensoLyte® Thioflavin T [Pyr3] - β-Amyloid (3-42) Aggregation Kit (Cat. AS-72276). Aggregation is guaranteed. The quantity is 0.25mg net peptide. [Pyr3] - β-Amyloid (3-42)   is the predominant amyloid peptide found in human brain, which causes Alzheimer’s disease and Down’s Syndrome. The Pyro-Glu modification on the N-terminal of β-amyloid (3-42) provides resistance to degradation. It also has higher toxicity and aggregation propensity compared to non-modified beta-amyloid. 


Specifications

Chemistry
Sequence one letter code
  • Pyr-FRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA
Sequence three letter code
  • Pyr-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH
Molecular Formula
  • C196H299N53O55S
Molecular Mass/ Weight
  • 4310,2
Properties
Absorbance (nm)
  • 440
Emission (nm)
  • 484
Quantity & Purity
Purification Method
  • HPLC
Storage & stability
Form
  • Lyophilized
Resuspension condition
  • Reconstitute peptide in 1%NH4OH then 50mM Tris/150mM NaCl (pH 7.2). Use water bath sonicator to completely dissolve peptide if necessary. Do not vortex!
Storage Conditions
  • Store at - 20 °C. Do not freeze thaw reconsituted peptide.
Activity
Application
Biomarker Target
Research Area
Sub-category Research Area
Source
Source / Species
  • human