AggreSure [Pyr3] β-Amyloid (3-42), human - 0.25 mg

AggreSure™ [Pyr3] - β-Amyloid (3-42) peptide for Alzheimer's disease research is guaranteed to aggregate. Also called Pyroglutamate Aβ3-42, the peptide is pretreated and tested for aggregation using SensoLyte® Thioflavin T [Pyr3] - β-Amyloid (3-42) Aggregation Kit (Cat. AS-72276). The quantity provided is 0.25mg net peptide. 

Pyroglutamate Aβ3-42 makes up about a quarter of total Aβ in AD brain plaques. The Pyro-Glu modification on the N-terminal of β-amyloid (3-42) provides resistance to degradation. It has a higher propensity to aggregate compared to non-modified beta-amyloid and is associated with cellular toxicity and cognitive dysfunction.

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