Labeling-detection

DABCYL acid [4-((4-(dimethylamino)phenyl)azo)benzoic acid] UltraPure Grade - 1 g

  • Cat.Number : AS-81800
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    In stock

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DABCYL acid is the abbreviation of 4-(dimethylaminoazo)benzene-4-carboxylic acid. In some literature, DABSYL (4-dimethylaminoazobenzene-4''-sulfonyl chloride) is misused as ‘DABCYL’. DABCYL is one of the most popular acceptors for developing FRET-based nucleic acid probes and protease substrates. DABCYL dyes are often paired with EDANS in FRET-based fluorescent probes.

Specifications

Chemistry
CAS registry number
  • 6268-49-1
Molecular Formula
  • C15H15N3O2
Molecular Mass/ Weight
  • 269.3
Properties
Absorbance (nm)
  • 425
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Resuspension condition
  • DMF or DMSO
Storage Conditions
  • -20°C Protected from Light
Activity
Application
Research Area
Sub-category Research Area
Usage
  • Research use

References

A comparison of human immunodeficiency virus type-1 protease inhibition activities by the aqueous and methanol extracts of Chinese medicinal herbs

Life Sci . 2000 Oct 27 ; 67(23) 2889 | DOI : https://doi.org/10.1016/S0024-3205(00)00864-X

  • TL. Lam

A general method for the preparation of internally quenched fluorogenic protease substrates using solid-phase peptide synthesis.

J Med Chem . 1992 Oct 01 ; 35(21) 3727 | DOI : https://doi.org/10.1021/jm00099a001

  • LL. Maggiora
  • et al

PNA Beacons for Duplex DNA

Antisense Nucleic Acid Drug Dev . 2004 Jul 08 ; 11(4) 265 | DOI : https://doi.org/10.1089/108729001317022269

  • H. Kuhn
  • et al