Labeling-detection

DiI [1,1'-Dioctadecyl-3,3,3',3'-tetramethylindocarbocyanine iodide] - 100 mg

$131.00
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  • Cat.Number : AS-84711
  • Availability :
    In stock
  • Shipping conditions : Ice fees will apply

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DiI, DiO, DiD and DiR dyes are a family of lipophilic fluorescent dyes which stain membranes and other lipophilic molecules. Their fluorescence highly increases when incorporated into membranes or bound to lipophilic molecules. Once applied onto cells, they diffuse laterally within the membranes to stain the entire cells. Their fluorescence is significantly increased upon membrane incorporation. This family of dyes fluoresces at distinct colors: DiI (orange), DiO (green), DiD (red) and DiR (far red); so they are adapted to multicolor imaging and flow cytometric of living cells. DiO and DiI can be used with standard FITC and TRITC filters respectively.
DiI is frequently used due to its very low cell toxicity. It is also used to label lipoproteins such as LDL and HDL.

Specifications

Chemistry
Molecular Formula
  • C59H97N2•I
Molecular Mass/ Weight
  • 961.3
Properties
Absorbance (nm)
  • 549
Emission (nm)
  • 565
Color
Quantity & Purity
Purity
  • TLC major spot
Storage & stability
Form
  • Lyophilized
Resuspension condition
  • DMSO
Storage Conditions
  • -20°C Protected from Light
Activity
Application
Detection Method
Research Area
Sub-category Research Area
Usage
  • Research use

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Citations

Evaluation of corticospinal axon loss by fluorescent dye tracing in mice with experimental autoimmune encephalomyelitis.

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  • Z. Liu

Nuclear atrophy of retinal ganglion cells precedes the Bax-dependent stage of apoptosis.

Invest Ophthalmol Vis Sci . 2013 Mar 11 ; 54(3) 1805 | DOI : 10.1167/iovs.11-9310.

  • K. Janssen

References

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Correlation of the Thermal Stability of Phospholipid‐Based Emulsions and the Microviscosity Measurements Using Fluorescence Polarization

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Effects of Indocyanine Green on Retinal Ganglion Cells

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Fluorescence properties of Laurdan in cochleate phases

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Liposomal clodronate as a novel agent for treating autoimmune hemolytic anemia in a mouse model

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Morphogenesis of chicken liver: identification of localized growth zones and the role of β-catenin/Wnt in size regulation

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