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Peptides

Fmoc-Azidohomoalanine - 100 mg

$508.00
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  • Cat.Number : AS-63670
  • Availability :
    In production

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An unusual amino acid used in Solid Phase Peptide Synthesis (SPPS) for the synthesis of modifiable side-chain peptides and proteins.1 The side-chain azido (N3) group is stable in trifluoroacetic acid (TFA) and piperidine (Pip), two reagents commonly used in SPPS. The azido group can be readily converted to an amine on the solid phase or in solution via the Staudinger reduction.2 In addition, incorporation of azidohomoalanine into proteins has shown promise as an effective IR probe into local electrostatic environments of proteins.3

Specifications

Chemistry
CAS registry number
  • 942518-20-9
Molecular Formula
  • C19H18N4O4
Molecular Mass/ Weight
  • 366.3
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Storage Conditions
  • 4 °C
Activity
Usage
  • Research use

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References

Staudinger-Phosphonite Reactions for the Chemoselective Transformation of Azido-Containing Peptides and Proteins

Org. Lett. . 2011 Sep 29 ; 13(20) 5440 | DOI : https://doi.org/10.1021/ol2020175

  • M.R.J. Vallee
  • et al