Peptides
Fmoc-L-(2,6-di-Me)Tyr-OH
$307.00
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- Cat.Number : AS-63729-025
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2,6-dimethyl-tyrosine(Dmt) is chi-constrained α-amino acid, and its incorporation in strategic positions of peptides(local side-chain constraines) has allowed for a substantial reduction of the corresponding side-chain conformers.
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References
Large-scale asymmetric synthesis of novel sterically constrained 2′,6′-dimethyl- and α,2′,6′-trimethyltyrosine and -phenylalanine derivatives via alkylation of chiral equivalents of nucleophilic glycine and alanine
Tetrahedron . 2001 Jul 01 ; 57(30) 6375 | DOI : https://doi.org/10.1016/S0040-4020(01)00504-X
- VA. Soloshonok
- et al