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Peptides

Fmoc-L-propargylglycine

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  • Cat.Number : AS-26264-F1
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An unusual amino acid used in Solid Phase Peptide Synthesis (SPPS) as: A) a precursor to the tritium-induced Norvaline peptides1, B) in the synthesis of branched peptides using a palladium-catalyzed coupling reaction2, and C) as a reagent in the dual-catalyst Sonogashira coupling reaction.3

Specifications

Chemistry
CAS registry number
  • 198561-07-8
Molecular Formula
  • C20H17NO4
Molecular Mass/ Weight
  • 335.4
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Storage Conditions
  • 4 °C
Activity
Usage
  • Research use

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Citations

Synthesis and characterization of elastin−mimetic hybrid polymers with multiblock, alternating molecular architecture and elastomeric properties.

Macromolecules . 2010 Apr 01 ; 42(7)2532 | DOI : 10.1021/ma802791z

  • SE. Grieshaber

References

A convenient synthesis of acetylenes: catalytic substitutions of acetylenic hydrogen with bromoalkenes, iodoarenes and bromopyridines

Tetrahedron Lett. . 1975 Jan 01 ; 50 4467

  • K. Sonogashira
  • et al

Tritiation of Peptides to High Specific Radioactivity. Part 1. Synthesis and Biological Properties of [13-(3H4)Norvaline]-α-MSH and of [2,23-Bis((3H2)tyrosine)]ACTH(1–24)

Helvetica Chim. Acta. . 1985 Nov 13 ; 68(7) 1880 | DOI : https://doi.org/10.1002/hlca.19850680711

  • A.N. Eberle
  • A. Zeller

Palladium-catalyzed coupling of a propargylglycine derivative.

Tetrahedron . 1992 Apr 10 ; 48(15) 3239 | DOI : https://doi.org/10.1016/S0040-4020(01)92261-6

  • GT. Crisp
  • TA. Robertson