This is a fluorescent (HiLyte™ Fluor 488)-labeled ß-Amyloid peptide, Abs/Em=503/528 nm. Hilyte 488™ Fluor labeled Aß (1-42) has a brighter intensity than FAM-labeled Aß (1-42).
Solvent InformationFgure 1. Absoprtion and emission spectra of HiLyte™ Fluor 488 labeled β-Amyloid (1-42).
Figure 2. Staining pattern of HiLyte™ Fluor 488 labeled Aβ (1-42) peptide on an AD (A) and a normal brain (B). Images courtesy of Dr. Jian-Ping Guo in Dr. Patrick L. McGeer’s lab, University of British Columbia, Vancouver, Canada.
Hilyte™ Fluor488 - Asp - Ala - Glu - Phe - Arg - His - Asp - Ser - Gly - Tyr - Glu - Val - His - His - Gln - Lys - Leu - Val - Phe - Phe - Ala - Glu - Asp - Val - Gly - Ser - Asn - Lys - Gly - Ala - Ile - Ile - Gly - Leu - Met - Val - Gly - Gly - Val - Val - Ile - Ala - OH