IMG-EN-AS-60841-01.jpg
Peptides

Caspase 1 (ICE) Inhibitor II, biotinylated - 1 mg

$84.00
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  • Cat.Number : AS-60841
  • Availability :
    In stock

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Caspase1 Inhibitor II is also known as IL-1β Converting Enzyme (ICE) Inhibitor; Biotin-YVAD-CMK rescues neuronal cells from cell death in response to oxidative stress and oxygen/glucose deprivation.

Specifications

Chemistry
Sequence one letter code
  • Biotin-YVAD-CMK
Sequence three letter code
  • Biotin-Tyr-Val-Ala-Asp-Chloromethyl Ketone
Molecular Formula
  • C32H45ClN6O9S
Molecular Mass/ Weight
  • 725.3
Modification
Conjugation type
  • Biotins
Modification Name
Conjugation
  • Conjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Application
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use

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References

Interchain Proteolysis, in the Absence of a Dimerization Stimulus, Can Initiate Apoptosis-associated Caspase-8 Activation

J Biol Chem . 2004 Aug 01 ; 279(35) 36916 | DOI : https://doi.org/10.1074/jbc.M402039200

  • B. Murphy
  • et al

Spontaneous Human Monocyte Apoptosis Utilizes a Caspase-3-Dependent Pathway That Is Blocked by Endotoxin and Is Independent of Caspase-1

J. Immunol. . 1999 Aug 15 ; 163(4) 1755 | DOI : 10438906

  • R. Fahy
  • et al