Caspase 9 Substrate 1, chromogenic - 5 mg
- Cat.Number : AS-25278-5
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Alternative choices
Caspase-9 substrate;
pNA (4-nitroaniline)-derived caspase substrates are widely used for the colorimetric detection of various caspase activities. Cleavage of pNA peptides by caspases generates pNA that is monitored colorimetrically at ~405 nm. pNA has maximum absorption around 408 nm.
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Citations
Synergism of Rana catesbeiana ribonuclease and IFN-γ triggers distinct death machineries in different human cancer cells.
FEBS Lett . 2005 Jan 03 ; 579(1) 265 | DOI : 10.1016/j.febslet.2004.11.086
- C-HA. Tang
Arsenic and fluoride induce neural progenitor cell apoptosis.
Toxicol Lett . 2011 Mar 23 ; 203(3) 237 | DOI : 10.1016/j.toxlet.2011.03.023.
- R. Rocha
References
Substrate specificities of caspase family proteases.
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- RV. Talanian
- et al
Activation of the CPP32 protease in apoptosis induced by 1-ß-D-arabinofuranosylcytosine and other DNA-damaging agents
Blood . 1996 Sep 15 ; 88(6) 1936 | DOI : https://doi.org/10.1182/blood.V88.6.1936.bloodjournal8861936
- R. Datta
- et al
Apoptosis and its clinical impact
Head Neck . 2001 May 01 ; 23(5) 409 | DOI : https://doi.org/10.1002/hed.1052
- BR. Gastman
- et al
Caspase 8: an efficient method for large-scale autoactivation of recombinant procaspase 8 by matrix adsorption and characterization
Protein Expr Purif . 2002 May 25 ; 18(3) 378 | DOI : https://doi.org/10.1006/prep.2000.1205
- KA. Koeplinger
- et al
Caspases: enemies within.
Science . 1998 Aug 28 ; 281(5381 1312 | DOI : 10.1126/science.281.5381.1312
- NA Thornberry
- Y. Lazebnik
Caspases: key players in programmed cell death
Curr Opin Struct Biol . 2000 Dec 01 ; 10(6) 649 | DOI : https://doi.org/10.1016/S0959-440X(00)00146-9
- MG. Grutter
- et al
Catalytic properties of the caspases
Cell Death Differ . 1999 Nov 24 ; 6 1054 | DOI : https://doi.org/10.1038/sj.cdd.4400599
- HR. Stennicke
- GS. Salvesen
Enzymatic activity of two caspases related to interleukin-1beta-converting enzyme.
Eur J Biochem . 1998 Apr 01 ; 253(1) 76 | DOI : https://doi.org/10.1046/j.1432-1327.1998.2530076.x
- F. Fassy
- et al
Properties of the caspases
Biochim Biophys Acta . 1998 Nov 24 ; 1387(1-2) 17 | DOI : https://doi.org/10.1016/S0167-4838(98)00133-2
- HR. Stennicke
- GS. Salvesen