Cetrorelix Acetate, Cetrotide - 1 mg
- Cat.Number : AS-60869
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A highly modified luteinizing hormone-releasing hormone (LHRH) decapeptide with a terminal amide group, this peptide is a LHRH antagonist. It regulates the expression of Galphas and Galphai protein subunits and adenylate cyclase activity in ovary, breast and pituitary. Cetrorelix competitively inhibits LHRH receptor in the pituitary gland to suppress ovarian and testicular functions.
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References
Luteinizing hormone-releasing hormone antagonist Cetrorelix regulates the expression of Gαs and Gαi protein subunits and adenylate cyclase activity in rat ovary, breast and pituitary
Intl J Oncol . 2004 Mar 01 ; 24(3) 725 | DOI : https://doi.org/10.3892/ijo.24.3.725
- B. Collado
- et al
Disposition and Metabolism of Cetrorelix, A Potent Luteinizing Hormone-Releasing Hormone Antagonist, in Rats and Dogs
Drug Metabolism and Disposition . 2000 Jan 01 ; 28(1) 10-20 | DOI : PMID: 10611134
- M. Schwahn
- et al