IMG-EN-AS-24281-01.jpg
Peptides

Conantokin G - 0.5 mg

$296.00
Check your price
  • Cat.Number : AS-24281
  • Availability :
    In production

Quantity

Add to wishlist Bulk Quote

Conantokin G (Con G) toxin is a 17-amino-acid competitive antagonist of N-methyl-D-aspartate (NMDA) receptors. It was isolated from the venom of Conus geographus and it belongs to a unique family of g-carboxyglutamic acid-containing Conus peptides.

Specifications

Chemistry
Sequence one letter code
  • GE(Gla)(Gla)LQ(Gla)NQ(Gla)LIR(Gla)KSN-NH2
Sequence three letter code
  • H-Gly-Glu-Gla-Gla-Leu-Gln-Gla-Asn-Gln-Gla-Leu-Ile-Arg-Gla-Lys-Ser-Asn-NH2
CAS registry number
  • 133628-78-1
Molecular Formula
  • C88H137N25O45
Molecular Mass/ Weight
  • 2264.4
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • Snail

Downloads

You may also be interested in the following product(s)

IMG-EN-AS-62604-01.jpg

Caloxin 2A1 - 1 mg

Cat.Number : AS-62604
$141.00 Excl. Tax
IMG-EN-AS-60763-01.jpg

Iberiotoxin (IbTX) - 0.1 mg

Cat.Number : AS-60763
$204.00 Excl. Tax
IMG-EN-AS-22926-01.jpg

ω-Conotoxin GVIA

Cat.Number : AS-22926
$296.00 Excl. Tax

References

Calcium binding mode of γ-carboxyglutamic acids in conantokins

Prot Eng . 1999 Jul 01 ; 12(7) 589 | DOI : https://doi.org/10.1093/protein/12.7.589

  • C. Lin
  • et al

Conantokin G Is an NR2B-Selective Competitive Antagonist ofN-Methyl-d-aspartate Receptors

Mol Pharmacol . 2000 Sep 01 ; 58(3) 614 | DOI : https://doi.org/10.1124/mol.58.3.614

  • S. Donevan
  • R. McCabe

Conantokin-G selectively inhibits N-methyl-D-aspartate-induced currents in Xenopus oocytes injected with mouse brain mRNA

Euro J Pharmacol . 1992 Jul 01 ; 226(3) 239 | DOI : https://doi.org/10.1016/0922-4106(92)90067-6

  • L. Hammerland
  • et al

Determination of the Solution Structures of Conantokin-G and Conantokin-T by CD and NMR Spectroscopy

JBC . 1997 Jan 01 ; 272(4) 2299 | DOI : https://doi.org/10.1074/jbc.272.4.2291

  • N. Skjærbæk
  • et al

NMDA-receptor antagonist requirements in conantokin-G

FEBS Lett. . 1998 Sep 18 ; 435(2-3) 257 | DOI : https://doi.org/10.1016/S0014-5793(98)01077-1

  • T. Blandl
  • et al