Labeling-detection

DiBAC4(3) [Bis-(1,3-dibutylbarbituric acid)trimethine oxonol] UltraPure Grade - 25 mg

$263.00
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  • Cat.Number : AS-84700
  • Availability :
    In production
  • Shipping conditions : Ice fees will apply

Quantity

Sensitive 488 nm-excitable membrane potential probe, ~1% fluorescence intensity change/mV; Sensitivity is temperature-dependent.
When DiBAC4(3) enters into cells, it can bind to intracellular proteins or membrane and fluorescence. Upon cell depolarization, there is an additional influx of the dye and fluorescence increase. On the opposite, cell polarization shows a decrease in fluorescence.

Specifications

Chemistry
CAS registry number
  • 70363-83-6
Molecular Formula
  • C27H40N4O6
Molecular Mass/ Weight
  • 516.6
Properties
Absorbance (nm)
  • 493
Emission (nm)
  • 516
Color
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Resuspension condition
  • DMSO
Storage Conditions
  • -20°C Protected from Light
Activity
Application
Detection Method
Research Area
Sub-category Research Area
Usage
  • Research use

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Citations

A real-time screening assay for GIRK 1/4 channel blockers.

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  • K.B. Walsh

Suppression of Antimicrobial Peptide Expression by Ureaplasma Species.

Infect Immun . 2014 Feb 03 ; 82(4) 1657 | DOI : 10.1128/IAI.01231-13.

  • L. Xiao

Dual fluorochrome flow cytometric assessment of yeast viability.

Current Microbiol . 2010 Jan 05 ; 61(1) 57 | DOI : 10.1007/s00284-009-9576-7

  • B. Hernlem

A real-time screening assay for GIRK 1/4 channel blockers.

J Biomol Screen . 2010 Oct 11 ; 15(10) 1229 | DOI : 10.1177/1087057110381384

  • K.B. Walsh

References

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Divalent cations increase lipid order in erythrocytes and susceptibility to secretory phospholipase A2

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Effects of Indocyanine Green on Retinal Ganglion Cells

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Fluorescence properties of Laurdan in cochleate phases

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Differential adaptation of membranes of two osmotolerant fungi, Aspergillus chevalieri and Penicillium expansum to high sucrose concentrations

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High-throughput Morphometric Analysis of Individual Neurons

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Liposomal clodronate as a novel agent for treating autoimmune hemolytic anemia in a mouse model

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Morphogenesis of chicken liver: identification of localized growth zones and the role of β-catenin/Wnt in size regulation

Dev Biol . 2004 Feb 01 ; 266(1) 109 | DOI : https://doi.org/10.1016/j.ydbio.2003.10.010

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Real-time measurements of dissolved oxygen inside live cells by organically modified silicate fluorescent nanosensors

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