DiBAC4(3) [Bis-(1,3-dibutylbarbituric acid)trimethine oxonol] UltraPure Grade - 25 mg
- Cat.Number : AS-84700
- Manufacturer Ref. :
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In production
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Sensitive 488 nm-excitable membrane potential probe, ~1% fluorescence intensity change/mV; Sensitivity is temperature-dependent.
When DiBAC4(3) enters into cells, it can bind to intracellular proteins or membrane and fluorescence. Upon cell depolarization, there is an additional influx of the dye and fluorescence increase. On the opposite, cell polarization shows a decrease in fluorescence.
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Citations
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A real-time screening assay for GIRK 1/4 channel blockers.
J Biomol Screen . 2010 Oct 11 ; 15(10) 1229 | DOI : 10.1177/1087057110381384
- K.B. Walsh
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