Peptides

GIP (6-30), human, 1mg

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  • Cat.Number : AS-65661
  • Availability :
    In stock

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GIP (Glucose-dependent Insulinotropic Polypeptide or also known as Gastric Inhibitory Polypeptide) is a 42-amino acid peptide released by the K cells of the duodenum and jejunum in response to food intake. GIP (6-30) is a short active version of the 42-amino acid long peptide. Together with GLP (Gastric-like Peptide) these peptides are members of the hormone peptide family of incretins which stimulate insulin secretion from pancreatic islet β-cells, and also appears to promote beta cell proliferation and beta cell survival. Recent studies suggest that GIP plays a role in lipid homeostasis and possibly in the pathogenesis of obesity.

Specifications

Chemistry
Sequence one letter code
  • FISDYSIAMDKIHQQDFVNWLLAQK-OH
Sequence three letter code
  • Phe-Ile-Ser-Asp-Tyr-Ser-Ile-Ala-Met-Asp-Lys-Ile-His-Gln-Gln-Asp-Phe-Val-Asn-Trp-Leu-Leu-Ala-Gln-Lys-OH
CAS registry number
  • 1139691-72-7
Molecular Formula
  • C139H208N34O39S1
Molecular Mass/ Weight
  • 3011.44
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human