[Glu1]-Fibrinopeptide B - 1 mg
- Cat.Number : AS-60501-1
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This peptide is derived from fibrinopeptide B amino acid residues 1-14. It is used as a mass spec (MS) standard in proteomic research.
Pyroglutamyl (pGlu) peptides may spontaneously form when either Glutamine (Q) or Glutamic acid (E) is located at the sequence N-terminus. The conversion of Q or E to pGlu is a natural occurrence and in general it is believed that the hydrophobic γ-lactam ring of pGlu may play a role in peptide stability against gastrointestinal proteases. Pyroglutamyl peptides are therefore considered a normal subset of such peptides and are included as part of the peptide purity during HPLC analysis.
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Citations
Elucidation of thioredoxin target protein networks in mouse.
Mol. Cell. Proteomics . 2009 May 04 ; 8(7) 1674 | DOI : 10.1074/mcp.M800580-MCP200
- C. Fu