Labeling-detection

Pentoxyresorufin - 5 mg

  • Cat.Number : AS-85728
  • Availability :
    In production

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Quantity

Resorufin pentyl ether is a fluorogenic cytochrome P-450 substrate that generates red fluorescent product upon enzyme cleavage

Specifications

Chemistry
CAS registry number
  • 87687-03-4
Molecular Formula
  • C17H17NO3
Molecular Mass/ Weight
  • 283.3
Properties
Absorbance (nm)
  • 571
Emission (nm)
  • 585
Color
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Resuspension condition
  • DMSO
Storage Conditions
  • -20°C Protected from Light
Activity
Application
Biomarker Target
Detection Method
Research Area
Sub-category Research Area
Usage
  • Research use

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References

A Direct, Highly Sensitive Fluorometric Assay for a Microsomal Cytochrome P450-Mediated O-Demethylation Using a Novel Coumarin Analog as Substrate

Z Naturforsch [C] . 2000 Nov 01 ; 55(11-12) 915 | DOI : https://doi.org/10.1515/znc-2000-11-1212

  • R. Roser
  • H. Thomas

Coumarin Substrates for Cytochrome P450 2D6 Fluorescence Assays

Anal Biochem . 2001 May 15 ; 292(2) 280 | DOI : https://doi.org/10.1006/abio.2001.5098

  • K. Nakamura
  • et al

Design and synthesis of a new fluorescent probe for cytochrome P450 3A4 (CYP 3A4)

Bioorg Med Chem Lett . 2003 Nov 03 ; 13(21) 3643 | DOI : https://doi.org/10.1016/j.bmcl.2003.08.027

  • A. Chougnet
  • et al

FLUORESCENCE-BASED ASSAYS FOR SCREENING NINE CYTOCHROME P450 (P450) ACTIVITIES IN INTACT CELLS EXPRESSING INDIVIDUAL HUMAN P450 ENZYMES

Drug Metab Dispos . 2004 Jul 01 ; 32(7) 699 | DOI : https://doi.org/10.1124/dmd.32.7.699

  • MT. Donato
  • et al

Fluorescent probes for cytochrome p450 structural characterization and inhibitor screening

J Am Chem Soc . 2002 Aug 10 ; 124(35) 10254 | DOI : https://doi.org/10.1021/ja0271678

  • AR. Dunn
  • et al

Inhibition of cytochrome P450 isozymes by curcumins in vitro and in vivo

Food Chem Toxicol . 2001 Jun 01 ; 39(6) 541 | DOI : https://doi.org/10.1016/S0278-6915(00)00165-4

  • R. Thapliyal
  • GB. Maru

The effect of reciprocal active site mutations in human cytochromes P450 1A1 and 1A2 on alkoxyresorufin metabolism

Arch Biochem Biophys . 2004 Apr 01 ; 424(1) 33 | DOI : https://doi.org/10.1016/j.abb.2003.12.040

  • J. Liu
  • et al

Probing the active site of cytochrome P450 2B1: metabolism of 7-alkoxycoumarins by the wild type and five site-directed mutants

Biochem . 1998 Apr 22 ; 37(19) 6679 | DOI : https://doi.org/10.1021/bi9731450

  • Y. Kobayashi
  • et al