SensoLyte® 490 MMP-2 Assay Kit Fluorimetric - 1 kit
- Cat.Number : AS-71129
- Manufacturer Ref. :
-
Availability :
In stock
- Shipping conditions : Ice fees will apply
Alternative choices
Matrix metalloproteinases (MMPs) belong to a family of secreted or membrane-associated proteins capable of digesting extracellular matrix components. The importance of MMPs in tumor development and invasion is well known. MMP-2 (gelatinase A) is proposed as a potential therapeutic target.
The SensoLyte® 490 MMP-2 Assay Kit is a complete assay system designed to continuously analyze MMP activities or to screen MMP-2 inhibitors by using a fluorogenic MMP-2 substrate.
Members of the MMP family have poor substrate sequence specificity, making it difficult to use a peptide substrate alone to differentiate the activity of a particular MMP from other MMPs. If several MMPs are coexisting in your samples and you would like to specifically measure MMP-2 activity, please choose the SensoLyte® Plus MMP-2 Assay Kit, Cat# AS-72224.
Specifications
Packaging | |
Kits components |
|
---|---|
Chemistry | |
UniProt number |
|
Properties | |
Absorbance (nm) |
|
Emission (nm) |
|
Storage & stability | |
Storage Conditions |
|
Activity | |
Application | |
Biomarker Target | |
Detection Method | |
Research Area | |
Sub-category Research Area | |
Usage |
|
Downloads
You may also be interested in the following product(s)
Citations
Structure-function studies on inhibitory activity of Bungarus multicinctus protease inhibitor-like protein on matrix metalloprotease-2, and invasion and migration of human neuroblastoma SK-N-SH cells.
Toxicon. . 2009 Aug 23 ; 55(2-3) 353 | DOI : 10.1016/j.toxicon.2009.08.012
- W. Chou
ERK1/2 activation induced by inflammatory cytokines compromises effective host tissue integration of engineered cartilage
Tissue Eng Part A . 2008 Jan 01 ; 15(10) 2825 | DOI : 10.1089/ten.TEA.2008.0663
- F. Djouad
Chlorotyrosine promotes human aortic smooth muscle cell migration through increasing superoxide anion production and ERK1/2 activation
Atherosclerosis. . 2008 Feb 20 ; 201(1) 37 | DOI : 10.1016/j.atherosclerosis.2007.12.049
- H. Mu
The inhibitory effects of silver diamine fluoride at different concentrations on matrix metalloproteinases
Dent Mater. . 2012 May 12 ; 28(8) 903 | DOI : 10.1016/j.dental.2012.04.011
- M.L. Mei
Homocysteine-Enhanced Proteolytic and Fibrinolytic Processes in Thin Intraluminal Thrombus and Adjacent Wall of Abdominal Aortic Aneurysm: Study In Vitro.
Biomed Res Int . 2018 Dec 12 ; 2018 3205324 | DOI : https://doi.org/10.1155/2018/3205324
- A. Siennicka
- et al
4F2hc-silencing impairs tumorigenicity of HeLa cells via modulation of galectin-3 and β-catenin signaling, and MMP-2 expression.
Biochim Biophys Acta . 2013 Sep 01 ; 1833(9) 2045 | DOI : https://doi.org/10.1016/j.bbamcr.2013.04.017
- A. Santiago-Gómez
- et al