SensoLyte® AFC Caspase Substrate Sampler Kit Fluorimetric - 1 kit
- Cat.Number : AS-71117
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Caspases play important roles in apoptosis and cell signaling. They are also identified as drug-screening targets. AFC-based substrates yield blue fluorescence upon protease cleavage (Ex/Em=380 nm/500 nm). They are widely used to monitor caspase activity.
The SensoLyte® Caspase Substrate Kit contains a series of AFC-based peptide substrates as fluorogenic indicators for assaying caspase protease activities. It provides the best solution for identifying a suitable substrate for designing AFC-based caspase assays. All the components in the kit are available in bulk package.
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Citations
Induction of apoptosis pathways in several cell lines following exposure to the marine algal toxin Azaspiracid
Chem Res Toxicol. . 2012 Jul 02 ; 25(7) 1493 | DOI : 10.1021/tx3001785
- M.J. Twiner
The proapoptotic activity of the Interferon-inducible gene IFI16 provides new insights into its etiopathogenetic role in autoimmunity
J Autoimmun. . 2010 May 21 ; 35(2) 114 | DOI : 10.1016/j.jaut.2010.04.001
- F. Gugliesi