Peptides

Tau peptide (306-336) (Repeat3 domain) - 1 mg

  • Cat.Number : AS-65435-1
  • Availability :
    In stock

Quantity

TAU proteins belong to the microtubule-associated protein (MAP) family and are involved in the pathogenesis of Alzheimer’s disease. In the human brain, there are six TAU isoforms ranging from 352 to 441 amino acids in length. These isoforms vary at the carboxyl terminal according to the presence of either three repeat or four repeat domains (R1-R4), in addition to the presence or absence of one or two insert domains at the amino-terminus. Tau Peptide (306-336) is a 31-amino acid long peptide derived from the Repeat 3 domain.

Specifications

Chemistry
Sequence one letter code
  • VQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQ
Sequence three letter code
  • Val-Gln-Ile-Val-Tyr-Lys-Pro-Val-Asp-Leu-Ser-Lys-Val-Thr-Ser-Lys-Cys-Gly-Ser-Leu-Gly-Asn-Ile-His-His-Lys-Pro-Gly-Gly-Gly-Gln-OH
Molecular Formula
  • C143H236N42O42S
Molecular Mass/ Weight
  • 3248
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human

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References

Domains of tau protein, differential phosphorylation, and dynamic instability of microtubules.

Mol Biol Cell . 1995 Dec 01 ; 6(12) 1887 | DOI : https://doi.org/10.1091/mbc.6.12.1887

  • B. Trinczek
  • et al

Tau protein isoforms, phosphorylation and role in neurodegenerative disorders

Brain Res Rev . 2000 Aug 01 ; 33(1) 95 | DOI : https://doi.org/10.1016/S0165-0173(00)00019-9

  • L. Buee
  • et al