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Peptides

W Peptide, WKYMVm - NH2 - 1 mg

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  • Cat.Number : AS-27069
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This peptide, containing the consensus sequence XKYX(P/V)M, is found to stimulate phospholipase C (PLC)-mediated formation of InoPs in certain cell lines and human neutrophils. WKYMVm-NH2 may have the ability to activate the microbicidal functions of human neutrophils.

Specifications

Chemistry
Sequence one letter code
  • WKYMVm-NH2
Sequence three letter code
  • Trp-Lys-Tyr-Met-Val-D-Met-NH2
CAS registry number
  • 187986-11-4
Molecular Formula
  • C41H61N9O7S2
Molecular Mass/ Weight
  • 856.1
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use

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References

A peptide with unique receptor specificity: stimulation of phosphoinositide hydrolysis and induction of superoxide generation in human neutrophils.

J Immunol . 1997 Feb 15 ; 158(4) 1895 | DOI : 9029131

  • J. Seo
  • et al

Identification of the Peptides That Stimulate the Phosphoinositide Hydrolysis in Lymphocyte Cell Lines from Peptide Libraries

J Biol Chem . 1996 Apr 01 ; 271(14) 8170 | DOI : https://doi.org/10.1074/jbc.271.14.8170

  • S. Baek
  • et al

The Immunostimulatory Peptide WKYMVm-NH2 Activates Bone Marrow Mouse Neutrophils via Multiple Signal Transduction Pathways

Scand. J. Immunol. . 2005 Aug 10 ; 62(2) 140 | DOI : https://doi.org/10.1111/j.1365-3083.2005.01651.x

  • R. Boxio
  • et al