IMG-EN-AS-62638-01.jpg
Peptides

WRW4, Formyl Peptide Receptor-Like 1 (FPRL1) Antagonist - 1 mg

$92.00
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  • Cat.Number : AS-62638
  • Availability :
    In production

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This peptide inhibits binding of one of formyl peptide receptor-like 1 (FPRL1) agonists WKYMVm to its specific receptor. FPRL1 is an important classical chemoattractant receptor that is expressed in phagocytic cells in the peripheral blood and brain. Activation of FPRL1 is closely related to inflammatory responses in the host defense mechanism and neurodegenerative disorders.

Specifications

Chemistry
Sequence one letter code
  • WRWWWW
Sequence three letter code
  • H-Trp-Arg-Trp-Trp-Trp-Trp-OH
Molecular Formula
  • C61H64N14O7
Molecular Mass/ Weight
  • 1105.3
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use

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Citations

Annexin A1 modulates macula densa function by inhibiting cyclooxygenase 2

Am J Physiol Renal Physiol. . 2012 Jul 11 ; 303(6) F845 | DOI : 10.1152/ajprenal.00704.2011

  • S. Seidel

Cathelicidin LL-37 increases lung epithelial cell stiffness, decreases transepithelial permeability, and prevents epithelial invasion by Pseudomonas aeruginosa

J Immunol. . 2011 Nov 16 ; 187(12) 6402 | DOI : 10.4049/jimmunol.1102185

  • FJ. Byfield

References

Identification of Peptides That Antagonize Formyl Peptide Receptor-Like 1-Mediated Signaling

J Immunol . 2004 Jul 01 ; 173(1) 607 | DOI : https://doi.org/10.4049/jimmunol.173.1.607

  • Y-S Bae
  • et al