Custom conjugation & labeling services
We specialize in the conjugation and labeling of proteins, peptides, and small molecules. Our extensive repository of conjugation & labeling reagents, includes a large selection of fluorescent proteins and fluorescent dyes that have been cited in high impact journals for their applications in research and drug discovery.
Protein and Peptide Conjugation
Our detection enzymes such as horseradish peroxidase (HRP) or alkaline phosphatase (AP) and fluorescent proteins enable conjugation with purified proteins or target-specific antibodies. Protein-to-protein conjugation is frequently used in immunoassays or imaging.
- Antibody - to - Enzyme (HRP)/Fluorescent Protein (RPE, BPE, APC)
- Streptavidin-to- Enzyme
We perform conjugations of carrier proteins to peptides for immune-functional studies via reactive maleimide or succinimidyl esters.
We offer conjugation to KLH, BSA, OVA for use in antibody (animal immunization) and vaccine development.
With expertise in peptide-antigen design, and peptide manufacturing from research to GMP grade, we can offer low bioburden and/or low endotoxin peptide conjugates. Available upon request.
- Fluorescent tags and their conjugates: Phycobiliproteins & Recombinant protein A
- Biotinylating reagents (targeting several functional groups),
- Streptavidins and conjugates.
The labeling and conjugation of proteins and small molecules are required in many experiments for monitoring and exploring extracellular and intracellular pathways applicable in a wide range of research and drug discovery applications.
In staining applications, reactive dyes confer direct binding ability with extracellular or intracellular proteins to facilitate tracking of biomolecules/processes at precise or diverse locations.
Figure: 3T3 cells stained with Rabbit anti-Tubulin IgG followed by Protein A-HiLyte™Fluor 488 (A) and Protein A-HiLyte™Fluor 647 (B).