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Fluorescent Dyes  >  Reactive Fluorescent Dyes  >>  Tetramethylrhodamine-5-maleimide

Product Name Tetramethylrhodamine - 5 - maleimide
Size 5 mg
Catalog # AS-81446
US$ $254

Maleimides are among the most frequently used reagents for thiol modification. In most proteins, the sites of reactions are at cysteine residues that either are intrinsically present or result from reduction of cystines. Unlike iodoacetamides, maleimides do not react with histidines and methionines under physiological conditions. Tetramethylrhodamine-5-maleimide is widely used for thiol modifications of peptides and proteins.

Detailed Information Material Safety Data Sheets (MSDS)
Storage -20C desiccated and protected from light
References 1. Graceffa P and Dominguez R (2003). J Biol Chem 278, 34172-80.
2. Tong Y, et al. (2001). J Gen Physiol 117, 103-18.
Molecular Weight 481.499
Molecular Formula C28H23 N3O5
Spectral Properties Abs/Em = 540/567 nm
Solvent System DMF or DMSO
Product Citations Iwamoto, M. & S. Oiki (2013). Amphipathic antenna of an inward rectifier K+ channel responds to changes in the inner membrane leaflet. PNAS 110, 749. doi: 10.1073/pnas.1217323110.

Srinivasan, S. et al. (2011). L-selectin transmembrane and cytoplasmic domains are monomeric in membranes. Biochim Biophys Acta-Biomembranes doi:10.1016/j.bbamem.2011.02.006.

Bakker, A. et al. (2008). Conditional MHC class I ligands and peptide exchange technology for the human MHC gene products HLA-A1, -A3, -A11, and -B7. PNAS 105, 3825.
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