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Labeling-detection

Tetramethylrhodamine-5-maleimide - 5 mg

$546.00
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  • Cat.Number : AS-81446
  • Availability :
    In production
  • Shipping conditions : Ice fees will apply

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Maleimides are among the most frequently used reagents for thiol modification. In most proteins, the sites of reactions are at cysteine residues that either are intrinsically present or result from reduction of cystines. Unlike iodoacetamides, maleimides do not react with histidines and methionines under physiological conditions. Tetramethylrhodamine-5-maleimide is widely used for thiol modifications of peptides and proteins.

Specifications

Chemistry
CAS registry number
  • 174568-67-3
Molecular Formula
  • C28H23N3O5
Molecular Mass/ Weight
  • 481.5
Properties
Absorbance (nm)
  • 540
Emission (nm)
  • 567
Color
Quantity & Purity
Purity
  • Peak Area by HPLC ≥90%
Storage & stability
Form
  • Lyophilized
Resuspension condition
  • DMF or DMSO
Storage Conditions
  • -20°C Protected from Light
Activity
Application
Detection Method
Research Area
Sub-category Research Area
Usage
  • Research use

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Citations

Conditional MHC class I ligands and peptide exchange technology for the human MHC gene products HLA-A1, -A3, -A11, and -B7.

PNAS . 2008 Mar 11 ; 105(10) 3825 | DOI : 10.1073/pnas.0709717105

  • A. Bakker

L-selectin transmembrane and cytoplasmic domains are monomeric in membranes.

Biochim Biophys Acta. . 2011 Jun 01 ; 1808(6)1709 | DOI : 10.1016/j.bbamem.2011.02.006.

  • S. Srinivasan

Amphipathic antenna of an inward rectifier K+ channel responds to changes in the inner membrane leaflet.

PNAS. . 2012 Dec 24 ; 110(2)749 | DOI : 10.1073/pnas.1217323110.

  • M. Iwamoto
  • S. Oiki

References

Crystal structure of monomeric actin in the ATP state. Structural basis of nucleotide-dependent actin dynamics

J Biol Chem . 2003 Sep 01 ; 278(36) 34172 | DOI : 10.1074/jbc.M303689200

  • P. Graceffa
  • R. Dominguez

Tyrosine decaging leads to substantial membrane trafficking during modulation of an inward rectifier potassium channel

J Gen Physiol . 2001 Feb 01 ; 117(2) 103 | DOI : 10.1085/jgp.117.2.103

  • Y. Tong
  • et al