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Assay Kits  >  MMP Assay Kits  >>  SensoLyte ® Plus 520 MMP-9 Assay Kit *Fluorimetric and Enhanced Selectivity*

Product Name SensoLyte ® Plus 520 MMP - 9 Assay Kit *Fluorimetric and Enhanced Selectivity*
Size 1 kit
Catalog # AS-72017
US$ $601

The SensoLyte® Plus 520 MMP-9 Assay Kit is designed for specifically detecting MMP-9 activity in biological samples which may contain multiple MMPs, such as culture medium, serum, plasma, synovial fluid, and tissue homogenate. A specific anti-MMP-9 monoclonal antibody is used in combination with a MMP fluorogenic substrate, 5-FAM/QXL®520 FRET peptide. The fluorescence signal is monitored at Ex/Em=490 nm/520 nm upon MMP-9-induced cleavage of the FRET substrate. Ample materials are provided to perform 96 assays in a 96-well format.

Detailed Information Datasheet
Material Safety Data Sheets (MSDS)
Product Citations Santos, JM. et al. (2013). Interrelationship between activation of matrix metalloproteinases and mitochondrial dysfunction in the development of diabetic retinopathy. Biochem Biophys Res Comm 438, 760.

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Woo, MS. et al.(2008). Inhibition of MMP-3 or -9 suppresses lipopolysaccharide-induced expression of proinflammatory cytokines and iNOS in microglia. J. Neurochem. doi:10.1111/j.1471-4159.2008.05430.x

Okawa, T. et al. (2007).The functional interplay between EGFR overexpression, hTERT activation, and p53 mutation in esophageal epithelial cells with activation of stromal fibroblasts induces tumor development, invasion, and differentiation. Genes Dev. 21, 2788. doi: 10.1101/gad.1544507

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Neill, T. et al. (2012). Decorin antagonizes the angiogenic network: concurrent inhibition of Met, hypoxia inducible factor 1α, vascular endothelial growth factor A, and induction of thrombospondin-1 and TIMP3. J. Biol. Chem. 287:5492.
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