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Peptides

alpha-Mating Factor Pheromone, yeast - 5 mg

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  • Cat.Number : AS-60221-5
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This tridecapeptide, an alpha-factor pheromone of Saccharomyces cerevisiae, induces conjugation in yeast by binding to Ste2p. Its cognate GPCR activates a G protein signal pathway that highly conserves with mammalian signaling pathways.

Specifications

Chemistry
Sequence one letter code
  • WHWLQLKPGQPMY
Sequence three letter code
  • H-Trp-His-Trp-Leu-Gln-Leu-Lys-Pro-Gly-Gln-Pro-Met-Tyr-OH
CAS registry number
  • 59401-28-4
Molecular Formula
  • C82H114N20O17S
Molecular Mass/ Weight
  • 1684.1
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • yeast

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References

Functional Characterization of an α-Factor-Like Sordaria macrospora Peptide Pheromone and Analysis of Its Interaction with Its Cognate Receptor in Saccharomyces cerevisiae

Eukaryot Cell . 2005 Apr 01 ; 4(4) 661 | DOI : 10.1128/EC.4.4.661-672.2005

  • S. Mayrhofer
  • S. Pöggeler

Identification of Residues of the Saccharomyces cerevisiae G Protein-coupled Receptor Contributing to α-Factor Pheromone Binding

J Biol Chem . 2001 Oct 01 ; 276(41) 37950 | DOI : https://doi.org/10.1074/jbc.M103579200

  • BK. Lee
  • et al