Histone deacetylase, HDAC substrate Ac - RGK(Ac) - AMC
% Peak Area By HPLC ≥ 95%
This novel fluorogenic substrate of HDACs was synthesized with an epsilon-acetylated lysyl moiety and an adjacent MCA moiety at the C-terminus of the peptide chain. The assay utilizing this substrate provides a good tool to characterize the HDAC activity. HDACs are important enzymes for the transcriptional regulation of gene expression.