IL-8 Inhibitor - 1 mg
- Cat.Number : AS-62401
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This hexapeptide, acetylated on the amino terminus and amidated on the carboxyl terminus, inhibits the specific binding of 125I-IL-8 to neutrophils. IL-8 is a member of the chemokine alpha subfamily that activates neutrophils and is chemotactic for these cells. IL-8 Inhibitor also suppresses the binding of macrophage inflammatory protein 2 (MIP 2) beta to neutrophils.
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Citations
Direct Elucidation of disulfide bond partners using ultraviolet photodissociation mass spectrometry.
Anal Chem . 2011 Aug 02 ; 83(17) 6455 | DOI : 10.1021/ac201650v
- A. Agarwal
Mechanism of neutrophil recruitment to the lung after pulmonary contusion.
Shock . 2011 Jun 01 ; 35(6) 604 | DOI : 10.1097/SHK.0b013e3182144a50
- JJ. Hoth
Effects of PARP-1 deficiency on airway inflammatory cell recruitment in response to LPS or TNF: differential effects on CXCR2 ligands and Duffy antigen receptor for chemokines.
J Leukocyte Biol . 2009 Sep 10 ; 86(6) 1385 | DOI : 10.1189/jlb.0309183
- M. Zerfaoui
References
Synthetic hexa- and heptapeptides that inhibit IL-8 from binding to and activating human blood neutrophils.
J. Immunol. . 1995 Jan 15 ; 154(2) 814 | DOI : PMID: 7814885
- S. Hayashi
- et al