IMG-EN-AS-63728-01-01.jpg
Peptides

ADAMTS-13 FRET Substrate, FRETS-VWF73

$441.00
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  • Cat.Number : AS-63728-01
  • Availability :
    In production

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FRETS-VWF73 is a very powerful Fluorescence-Quenching Substrate for the VWF cleaving protease ADAMTS-13. It is commonly used as a useful tool for the rapid measurement of ADAMTS-13 activity in plasma and is a predictive marker for various thrombotic diseases like TPP. Our new substrate FRETS-VWF73 can be easily used with a 96-well format in commercial plate readers.

Specifications

Chemistry
Sequence one letter code
  • DRE-Dap(Nma)-APNLVYMVTG-Dap(Dnp)-PASDEIKRLPGDIQVVPIGVGPNANVQELERIGWPNAPILIQDFETLPREAPDLVLQR
Sequence three letter code
  • H-Asp-Arg-Glu-Dap(Nma)-Ala-Pro-Asn-Leu-Val-Tyr-Met-Val-Thr-Gly-Dap(Dnp)-Pro-Ala-Ser-Asp-Glu-Ile-Lys-Arg-Leu-Pro-Gly-Asp-Ile-Gln-Val-Val-Pro-Ile-Gly-Val-Gly-Pro-Asn-Ala-Asn-Val-Gln-Glu-Leu-Glu-Arg-Ile-Gly-Trp-Pro-Asn-Ala-Pro-Ile-Leu-Ile-Gln-Asp-Phe-Glu-Thr-Leu-Pro-Arg-Glu-Ala-Pro-Asp-Leu-Val-Leu-Gln-Arg-OH
Molecular Mass/ Weight
  • 8314.9
Properties
Absorbance (nm)
  • 340
Emission (nm)
  • 440
Modification
Conjugation type
  • Spacers
Modification Name
Conjugation
  • Conjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C Protected from light
Activity
Application
Biomarker Target
Detection Method
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human

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References

FRETS‐VWF73, a first fluorogenic substrate for ADAMTS13 assay

Br. J. Haematol . 2005 Mar 21 ; 129(1) 93 | DOI : https://doi.org/10.1111/j.1365-2141.2005.05420.x

  • K. Kokame
  • et al