IMG-EN-AS-60447-01.jpg
Peptides

Adrenomedullin (1-52), human - 0.5 mg

$450.00
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  • Cat.Number : AS-60447
  • Availability :
    In stock

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Adrenomedullin (AM or ADM) is a 52-amino acid peptide initially isolated from pheochromyctoma, a tumor of the adrenal medulla, hence the name 'Adrenomedullin.' Growing evidence shows that Adrenomedullin has many biological action which includes vasodilatation, cell growth, regulation of hormone secretion, natriuresis, as well as possessing antimicrobial effects.

Specifications

Chemistry
Sequence one letter code
  • YRQSMNNFQGLRSFGCRFGTCTVQKLAHQIYQFTDKDKDNVAPRSKISPQGY-NH2 (Disulfide bridge: 16-21)
Sequence three letter code
  • H-Tyr-Arg-Gln-Ser-Met-Asn-Asn-Phe-Gln-Gly-Leu-Arg-Ser-Phe-Gly-Cys-Arg-Phe-Gly-Thr-Cys-Thr-Val-Gln-Lys-Leu-Ala-His-Gln-Ile-Tyr-Gln-Phe-Thr-Asp-Lys-Asp-Lys-Asp-Asn-Val-Ala-Pro-Arg-Ser-Lys-Ile-Ser-Pro-Gln-Gly-Tyr-NH2 (Disulfide bridge: 16-21)
CAS registry number
  • 148498-78-6
Molecular Formula
  • C264H406N80O77S3
Molecular Mass/ Weight
  • 6029.1
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human

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Citations

Pathogenesis of Pancreatic Cancer Exosome-Induced Lipolysis in Adipose Tissue.

Gut . 2015 Apr 28 ; 65(7) 1165 | DOI : 10.1136/gutjnl-2014-308350

  • G. Sagar

References

Adrenomedullin, a Multifunctional Regulatory Peptide

Endocrine Rev . 2000 Apr 01 ; 21(2) 138 | DOI : https://doi.org/10.1210/edrv.21.2.0396

  • JP. Hinson
  • et al

Adrenomedullin: A Novel Hypotensive Peptide Isolated from Human Pheochromocytoma

Biochem Biophys Res Commun . 1993 Mar 30 ; 192(2) 553 | DOI : https://doi.org/10.1006/bbrc.1993.1451

  • K. Kitamura
  • et al

Cell and molecular biology of the multifunctional peptide, adrenomedullin

International Review of Cytology . 2000 Jan 01 ; 221 1 | DOI : https://doi.org/10.1016/S0074-7696(02)21010-4

  • J. López
  • A. Martinez