Peptides

Bradykinin Antagonist, HOE I40 - 1 mg

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  • Cat.Number : AS-22968
  • Availability :
    In stock

Quantity

Hoe 140 is a stable B2 bradykinin antagonist. Based on its high potency and good tolerability, Hoe 140 is used to evaluate the role of bradykinin in human diseases.

Specifications

Chemistry
Sequence one letter code
  • rRP-(Hyp)-G-(Thi)-S-(D-Tic)-(Oic)-R
Sequence three letter code
  • H-D-Arg-Arg-Pro-Hyp-Gly-Thi-Ser-D-Tic-Oic-Arg-OH
CAS registry number
  • 130308-48-4
Molecular Formula
  • C59H89N19O13S
Molecular Mass/ Weight
  • 1304.5
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • Human, mouse, rat

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References

Bradykinin receptors.

Gen Pharmacol. . 1997 Jan 31 ; 28(1) 1 | DOI : 10.1016/s0306-3623(96)00174-7

  • JM. Hall
  • et al

Amelioration of hyperalgesia by kinin receptor antagonists or kininogen deficiency in chronic constriction nerve injury in rats

Inflamm Res . 2003 Apr 01 ; 52 164 | DOI : https://doi.org/10.1007/s000110300067

  • S. Yamaguchi-Sase
  • et al