Peptides

Angiotensin II, human, ClearPoint™ Ile labeled (13C and 15N) - 0.1 mg

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  • Cat.Number : AS-64805
  • Availability :
    In stock

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This peptide is angiontensin II (Ang II) with Isoleucine universally labeled with 13C and 15N. The octapeptide angiotensin II (Ang II) exerts a wide range of effects on the cardiovascular system. It is also implicated in the regulation of cell proliferation, fibrosis and apoptosis. Ang II is formed through cleavage of Ang I by the angiotensin-converting enzyme (ACE) or chymases. Human heart chymase, a chymotrypsin-like serine proteinase, hydrolyzes the Phe8-His9 bond to yield the octapeptide hormone angiotensin II and His-Leu.

Specifications

Chemistry
Sequence one letter code
  • DRVY-I*-HPF [I*= I(U13C6,15N)]
Sequence three letter code
  • H-Asp-Arg-Val-Tyr-*Ile-His-Pro-Phe-OH [Ile*= Ile(U13C6,15N)]
Molecular Formula
  • C50H71N13O12
Molecular Mass/ Weight
  • 1053.2
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • ≥ 95%
Storage & stability
Form
  • Lyophilized
Activity
Application
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human

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