IMG-EN-AS-60249-1-01.jpg
Peptides

Autocamtide-2 [KKALRRQETVDAL]

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  • Cat.Number : AS-60249-1
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The native peptide KKALRRQETVDAL is a selective substrate for Ca2+/calmodulin-dependent protein kinase (CaMK). The fluorescent and biotinylated peptides are used to design assays for CaMKs.

Specifications

Chemistry
Sequence one letter code
  • KKALRRQETVDAL
Sequence three letter code
  • H-Lys-Lys-Ala-Leu-Arg-Arg-Gln-Glu-Thr-Val-Asp-Ala-Leu-OH
CAS registry number
  • 129198-88-5
Molecular Formula
  • C65H118N22O20
Molecular Mass/ Weight
  • 1527.9
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Application
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use

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References

Ca2+-induced loss of Ca2+/calmodulin-dependent protein kinase II activity in pancreatic β-cells

Am J Physiol . 1998 Apr 01 ; 274(4) E708 | DOI : https://doi.org/10.1152/ajpendo.1998.274.4.E708

  • PM. Jones
  • SJ. Persaud

Calmodulin and calmodulin-dependent kinase II mediate neuronal cell death induced by depolarization

Brain Res . 2003 Feb 07 ; 962(1-2) 41 | DOI : https://doi.org/10.1016/S0006-8993(02)03932-X

  • H. Takano
  • et al

Long-lasting decrease in neuronal Ca2+/calmodulin-dependent protein kinase II activity in a hippocampal neuronal culture model of spontaneous recurrent seizures

Brain Res . 1999 Dec 18 ; 851(1-2) 54 | DOI : https://doi.org/10.1016/S0006-8993(99)02100-9

  • RE. Blair
  • et al