IMG-EN-AS-64929-01.jpg
Peptides

Autocamtide-2-Related Inhibitory Peptide (AIP); CaMKII Inhibitor, myristoylated - 1 mg

$172.00
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  • Cat.Number : AS-64929
  • Availability :
    In production

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This is a myristoylated form of Autocamtide-2-Related Inhibitory Peptide (AIP), a highly potent and specific substrate competitive inhibitor of Calmodulin-Dependent Protein Kinase ll (CaMKII). AIP is derived from Autocamtide-2, a substrate for CaMKII, with the Thr-9 phosphorylation site substituted with Ala.

Specifications

Chemistry
Sequence one letter code
  • Myr-KKALRRQEAVDAL
Sequence three letter code
  • Myr-Lys-Lys-Ala-Leu-Arg-Arg-Gln-Glu-Ala-Val-Asp-Ala-Leu-OH
Molecular Formula
  • C78H142N22O20
Molecular Mass/ Weight
  • 1708.2
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Application
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use

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References

Targeted Inhibition of Ca2+/Calmodulin-dependent Protein Kinase II in Cardiac Longitudinal Sarcoplasmic Reticulum Results in Decreased Phospholamban Phosphorylation at Threonine 17

J. Biol. Chem. . 2003 Jul 01 ; 278(27) 25063 | DOI : https://doi.org/10.1074/jbc.M302193200

  • Y. Ji
  • et al

Stabilization of Calmodulin-dependent Protein Kinase II through the Autoinhibitory Domain

J. Biol. Chem. . 1995 Feb 01 ; 270(5) 2163 | DOI : https://doi.org/10.1074/jbc.270.5.2163

  • A. Ishida
  • H. Fujisawa