IMG-EN-AS-22813-01.jpg
Peptides

Beta-Amyloid (17-40)

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  • Cat.Number : AS-22813-
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In Alheimer's Disease brains, plaques contain amino-terminal truncated beta-Amyloid peptides including the alpha secretase-generated p3 fragments, beta-Amyloid 17-40 and 17-42. They were shown to induce pro-inflammatory cytokine and chemokine production in vitro and in vivo.

Specifications

Chemistry
Sequence one letter code
  • LVFFAEDVGSNKGAIIGLMVGGVV
Sequence three letter code
  • H-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-OH
CAS registry number
  • 156790-69-1
Molecular Formula
  • C110H178N26O31S
Molecular Mass/ Weight
  • 2393
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human

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Citations

Identifying the minimal copper- and zinc-binding site sequence in amyloid-β peptides

J Biol Chem . 2008 Jan 30 ; 283(16) 10784 | DOI : 10.1074/jbc.M707109200

  • V. Minicozzi

Identifying the minimal Cu and Zn binding site sequence in amyloid beta peptides.

J Biol Chem . 2008 Jan 30 ; 283(16) 10784 | DOI : 10.1074/jbc.M707109200.

  • V. Minicozzi