Peptides

Biotin-beta-Amyloid (1-40)

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  • Cat.Number : AS-23512
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Aß (1-40) together with Aß (1-42) are two major C-terminal variants of the Aß protein constituting the majority of Aßs. These undergo post-secretory aggregation and deposition in the Alzheimer’s disease brain. This peptide is biotinylated at its N-terminus

Specifications

Chemistry
Sequence one letter code
  • Biotin-DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV
Sequence three letter code
  • Biotin-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-OH
CAS registry number
  • 183906-14-1
Molecular Formula
  • C204H309N55O60S2
Molecular Mass/ Weight
  • 4556.4
Modification
Conjugation type
  • Biotins
Modification Name
Conjugation
  • Conjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human

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Citations

Amyloid-β Peptide-specific DARPins as a Novel Class of Potential Therapeutics for Alzheimer Disease

J Biol Chem . 2014 Sep 26 ; 289(39) 27080 | DOI : 10.1074/jbc.M114.564013

  • M. Hanenberg

Specific binding of amyloid‐β‐protein to IMR‐32 neuroblastoma cell membrane

J Peptide Res . 2005 Apr 09 ; 65(5) 485 | DOI : 10.1111/j.1399-3011.2005.00250.x

  • S. Inaba

Cerebrospinal Aβ11-x and 17-x levels as indicators of mild cognitive impairment and patients’ stratification in Alzheimer’s disease.

Transl Psychiatry . 2013 Jul 16 ; 8 e281 | DOI : 10.1038/tp.2013.58.

  • JD. Abraham

Specific binding of amyloid-beta-protein to IMR-32 neuroblastoma cell membrane.

J Pept Res . 2005 May 01 ; 65(5) 485 | DOI : 10.1111/j.1399-3011.2005.00250.x

  • S. Inaba