IMG-EN-AS-23541-01.jpg
Peptides

Biotin-beta-Amyloid (17-40) - 1 mg

$740.00
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  • Cat.Number : AS-23541
  • Availability :
    In stock

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In Alheimer's Disease brains, plaques contain amino-terminal truncated beta-Amyloid peptides including the alpha secretase-generated p3 fragments, beta-Amyloid 17-40 and 17-42. They were shown to induce pro-inflammatory cytokine and chemokine production in vitro and in vivo. This peptide is biotinylated at the N-terminus.

Specifications

Chemistry
Sequence one letter code
  • Biotin-LVFFAEDVGSNKGAIIGLMVGGVV
Sequence three letter code
  • Biotin-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-OH
Molecular Formula
  • C120H192N28O33S2
Molecular Mass/ Weight
  • 2619.3
Modification
Conjugation type
  • Biotins
Modification Name
Conjugation
  • Conjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human

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References

Intervesicle Cross-Linking with Integrin αIIbβ3 and Cyclic-RGD-Lipopeptide. A Model of Cell-Adhesion Processes

Biochem . 2000 Sep 14 ; 39(40) 12284 | DOI : https://doi.org/10.1021/bi000144q

  • B. Hu
  • et al