Bradykinin; Angiotensin I Converting Enzyme (ACE I) Inhibitor
- Cat.Number : AS-20667
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This peptide is an inhibitor for Angiotensin I Converting Enzyme (ACE I), derived from Bradykinin. ACE I partially suppresses the renin-angiotensin-aldosterone system (RAAS), which regulates blood pressure and may mediate hypertension. ACE I converts angiotensin I to the biologically active peptide angiotensin II using a zinc- and chloride- dependent mechanism.
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Citations
The use of acetone as a substitute for acetonitrile in analysis of peptides by liquid chromatography/electrospray ionization mass spectrometry.
Rapid Comm Mass Spectrom . 2010 Jan 01 ; 24(1) 6 | DOI : 10.1002/rcm.4352
- T. Keppel
References
Blocking the RAAS at different levels: an update on the use of the direct renin inhibitors alone and in combination
Vasc Health Risk Manag . 2010 Aug 09 ; 6 549 | DOI : 10.2147/vhrm.s11816
- F. Cagnoni
- et al
Angiotensin-I-converting enzyme and its relatives
Genome Biol . 2003 Jul 25 ; 4 225 | DOI : https://doi.org/10.1186/gb-2003-4-8-225
- J. Riordan
- et al